Innate Immune Activation by Inhaled Lipopolysaccharide, Independent of Oxidative Stress, Exacerbates Silica-Induced Pulmonary Fibrosis in Mice

Acute exacerbations of pulmonary fibrosis are characterized by rapid decrements in lung function. Environmental factors that may contribute to acute exacerbations remain poorly understood. We have previously demonstrated that exposure to inhaled lipopolysaccharide (LPS) induces expression of genes a...

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Detalhes bibliográficos
Main Authors: Brass, David M., Spencer, Jennifer C., Li, Zhuowei, Potts-Kant, Erin, Reilly, Sarah M., Dunkel, Mary K., Latoche, Joseph D., Auten, Richard L., Hollingsworth, John W., Fattman, Cheryl L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397936/
https://ncbi.nlm.nih.gov/pubmed/22815821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040789
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