PinX1 suppresses tumorigenesis by negatively regulating telomerase/telomeres in colorectal carcinoma cells and is a promising molecular marker for patient prognosis

PinX1 plays positive and negative roles in the maintenance of telomerase and telomeres, as well as in tumorigenesis. The aim of the present study was to investigate the expression and clinical significance of PinX1 in colorectal carcinoma (CRC) and to determine the effect of PinX1 on CRC cell prolif...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Qian, Dong, Cheng, Jingjing, Ding, Xiaofeng, Chen, Xiuli, Chen, Xi, Guan, Yong, Zhang, Bin, Wang, Jiefu, Er, Puchun, Qiu, Minghan, Zeng, Xianliang, Guo, Yihang, Wang, Huanhuan, Zhao, Lujun, Xie, Dan, Yuan, Zhiyong, Wang, Ping, Pang, Qingsong
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976919/
https://ncbi.nlm.nih.gov/pubmed/27536146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S103141
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