PinX1 suppresses tumorigenesis by negatively regulating telomerase/telomeres in colorectal carcinoma cells and is a promising molecular marker for patient prognosis

PinX1 plays positive and negative roles in the maintenance of telomerase and telomeres, as well as in tumorigenesis. The aim of the present study was to investigate the expression and clinical significance of PinX1 in colorectal carcinoma (CRC) and to determine the effect of PinX1 on CRC cell prolif...

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Bibliografski detalji
Izdano u:Onco Targets Ther
Glavni autori: Qian, Dong, Cheng, Jingjing, Ding, Xiaofeng, Chen, Xiuli, Chen, Xi, Guan, Yong, Zhang, Bin, Wang, Jiefu, Er, Puchun, Qiu, Minghan, Zeng, Xianliang, Guo, Yihang, Wang, Huanhuan, Zhao, Lujun, Xie, Dan, Yuan, Zhiyong, Wang, Ping, Pang, Qingsong
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2016
Teme:
Original Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976919/
https://ncbi.nlm.nih.gov/pubmed/27536146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S103141
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