PinX1 suppresses tumorigenesis by negatively regulating telomerase/telomeres in colorectal carcinoma cells and is a promising molecular marker for patient prognosis

PinX1 plays positive and negative roles in the maintenance of telomerase and telomeres, as well as in tumorigenesis. The aim of the present study was to investigate the expression and clinical significance of PinX1 in colorectal carcinoma (CRC) and to determine the effect of PinX1 on CRC cell prolif...

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Publicat a:Onco Targets Ther
Autors principals: Qian, Dong, Cheng, Jingjing, Ding, Xiaofeng, Chen, Xiuli, Chen, Xi, Guan, Yong, Zhang, Bin, Wang, Jiefu, Er, Puchun, Qiu, Minghan, Zeng, Xianliang, Guo, Yihang, Wang, Huanhuan, Zhao, Lujun, Xie, Dan, Yuan, Zhiyong, Wang, Ping, Pang, Qingsong
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2016
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976919/
https://ncbi.nlm.nih.gov/pubmed/27536146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S103141
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