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Nanoscale studies link amyloid maturity with polyglutamine diseases onset
The presence of expanded poly-glutamine (polyQ) repeats in proteins is directly linked to the pathogenesis of several neurodegenerative diseases, including Huntington’s disease. However, the molecular and structural basis underlying the increased toxicity of aggregates formed by proteins containing...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4976327/ https://ncbi.nlm.nih.gov/pubmed/27499269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31155 |
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