Regional mapping of prion proteins in brain.

Scrapie is characterized by the accumulation of a protease-resistant isoform of the prion protein PrPSc. Limited proteolysis and chaotropes were used to map the distribution of PrPSc in cryostat sections of scrapie-infected brain blotted onto nitrocellulose membranes, designated histoblots. Proteoly...

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Bibliografiske detaljer
Main Authors: Taraboulos, A, Jendroska, K, Serban, D, Yang, S L, DeArmond, S J, Prusiner, S B
Format: Artigo
Sprog:Inglês
Udgivet: 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC49762/
https://ncbi.nlm.nih.gov/pubmed/1354357
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