Synthesis and trafficking of prion proteins in cultured cells.

Scrapie prions are composed largely, if not entirely, of the scrapie prion protein (PrPSc) that is encoded by a chromosomal gene. Scrapie-infected mouse neuroblastoma (ScN2a) and hamster brain (ScHaB) cells synthesize PrPSc from the normal PrP isoform (PrPC) or a precursor through a posttranslationa...

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Publié dans:	Mol Biol Cell
Auteurs principaux:	Taraboulos, A, Raeber, A J, Borchelt, D R, Serban, D, Prusiner, S B
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Cell Biology 1992
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC275644/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1356522/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.3.8.851
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