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Lineage specific effector signatures of iNKT cells are shared amongst γδ T, innate lymphoid, and T helper cells

Invariant natural killer T cells (iNKT) cells differentiate into three predominant effector lineages in the steady state. To understand these lineages, we sorted undifferentiated iNKT progenitor cells and each effector population, and analyzed their transcriptional profiles by RNAseq. Bioinformatic...

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Pubblicato in:J Immunol
Autori principali: Lee, You Jeong, Starrett, Gabriel J., Lee, Seungeun Thera, Yang, Rendong, Henzler, Christine M., Jameson, Stephen C., Hogquist, Kristin A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976040/
https://ncbi.nlm.nih.gov/pubmed/27385777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600643
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