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Ethanol and Other Short-Chain Alcohols Inhibit NLRP3 Inflammasome Activation through Protein Tyrosine Phosphatase Stimulation

Immunosuppression is a major complication of alcoholism that contributes to increased rates of opportunistic infections and sepsis in alcoholics. The NLRP3 inflammasome, a multi-protein intracellular pattern recognition receptor complex that facilitates the cleavage and secretion of the pro-inflamma...

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Dades bibliogràfiques
Publicat a:J Immunol
Autors principals: Hoyt, Laura R., Ather, Jennifer L., Randall, Matthew J., DePuccio, Daniel P., Landry, Christopher C., Wewers, Mark D., Gavrilin, Mikhail A., Poynter, Matthew E.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4975963/
https://ncbi.nlm.nih.gov/pubmed/27421477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600406
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