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Recombinant production of medium- to large-sized peptides in Escherichia coli using a cleavable self-aggregating tag

BACKGROUND: Peptides have recently become attractive for therapeutic applications. However, efficient production of medium- to large-sized peptides (30–100 amino acids [aa]) remains challenging both by recombinant and chemical synthesis. We previously reported the formation of active enzyme aggregat...

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Detalhes bibliográficos
Publicado no:Microb Cell Fact
Main Authors: Zhao, Qing, Xu, Wanghui, Xing, Lei, Lin, Zhanglin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4975908/
https://ncbi.nlm.nih.gov/pubmed/27495238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-016-0534-3
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