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Dicarbonyls and glyoxalase in disease mechanisms and clinical therapeutics
The reactive dicarbonyl metabolite methylglyoxal (MG) is the precursor of the major quantitative advanced glycation endproducts (AGEs) in physiological systems - arginine-derived hydroimidazolones and deoxyguanosine-derived imidazopurinones. The glyoxalase system in the cytoplasm of cells provides t...
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| Udgivet i: | Glycoconj J |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer US
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4975768/ https://ncbi.nlm.nih.gov/pubmed/27406712 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10719-016-9705-z |
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