Top-down Targeted Proteomics Reveals Decrease in Myosin Regulatory Light Chain Phosphorylation that Contributes to Sarcopenic Muscle Dysfunction

Sarcopenia, the loss of skeletal muscle mass and function with advancing age, is a significant cause of disability and loss of independence in the elderly, and, thus, represents a formidable challenge for the aging population. Nevertheless, the molecular mechanism(s) underlying sarcopenia-associated...

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Publicat a:J Proteome Res
Autors principals: Gregorich, Zachery R., Peng, Ying, Cai, Wenxuan, Jin, Yutong, Wei, Liming, Chen, Albert J., McKiernan, Susan H., Aiken, Judd M., Moss, Richard L., Diffee, Gary M., Ge, Ying
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4975644/
https://ncbi.nlm.nih.gov/pubmed/27362462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.6b00244
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