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Centrosomal Clustering Contributes to Chromosomal Instability and Cancer

Cells assemble mitotic spindles during each round of division to insure accurate segregation of their duplicated genome. In animal cells, stereotypical spindles have two poles, each containing one centrosome, from which microtubules are nucleated. In contrast, many cancer cells often contain more th...

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Dades bibliogràfiques
Publicat a:Curr Opin Biotechnol
Autors principals: Milunovic-Jevtic, A., Mooney, P., Sulerud, T., Bisht, J., Gatlin, J.C.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4975617/
https://ncbi.nlm.nih.gov/pubmed/27046071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.copbio.2016.03.011
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