CD8 T cells mediate direct biliary ductule damage in NOD autoimmune biliary disease

We previously described the NOD.c3c4 mouse, which is protected from type 1 diabetes (T1D) due to protective alleles at multiple insulin-dependent diabetes (Idd) genes, but develops autoimmune biliary disease (ABD) resembling primary biliary cirrhosis (PBC). Here we characterize the NOD.ABD strain, w...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Yang, Guo-Xiang, Wu, Yuehong, Tsukamoto, Hiroki, Leung, Patrick S., Lian, Zhe-Xiong, Rainbow, Daniel B., Hunter, Kara M., Morris, Gerard A., Lyons, Paul A., Peterson, Laurence B., Wicker, Linda S., Gershwin, M.E., Ridgway, William M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4975520/
https://ncbi.nlm.nih.gov/pubmed/21169553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001597
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