Induction of autoimmune cholangitis in non-obese diabetic (NOD).1101 mice following a chemical xenobiotic immunization

Our laboratory has suggested that loss of tolerance to pyruvate dehydrogenase (PDC-E2) leads to an anti-mitochondrial antibody response and autoimmune cholangitis, similar to human primary biliary cirrhosis (PBC). We have suggested that this loss of tolerance can be induced either via chemical xenob...

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Main Authors: Wakabayashi, K, Yoshida, K, Leung, P S C, Moritoki, Y, Yang, G-X, Tsuneyama, K, Lian, Z-X, Hibi, T, Ansari, A A, Wicker, L S, Ridgway, W M, Coppel, R L, Mackay, I R, Gershwin, M E
פורמט: Artigo
שפה:Inglês
יצא לאור: Blackwell Science Inc 2009
נושאים:
Animal Studies
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669535/
https://ncbi.nlm.nih.gov/pubmed/19094117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2008.03837.x
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