Simulated Microgravity and 3D Culture Enhance Induction, Viability, Proliferation and Differentiation of Cardiac Progenitors from Human Pluripotent Stem Cells

Efficient generation of cardiomyocytes from human pluripotent stem cells is critical for their regenerative applications. Microgravity and 3D culture can profoundly modulate cell proliferation and survival. Here, we engineered microscale progenitor cardiac spheres from human pluripotent stem cells a...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Jha, Rajneesh, Wu, Qingling, Singh, Monalisa, Preininger, Marcela K., Han, Pengcheng, Ding, Gouliang, Cho, Hee Cheol, Jo, Hanjoong, Maher, Kevin O., Wagner, Mary B., Xu, Chunhui
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4974658/
https://ncbi.nlm.nih.gov/pubmed/27492371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30956
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