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Simulated Microgravity and 3D Culture Enhance Induction, Viability, Proliferation and Differentiation of Cardiac Progenitors from Human Pluripotent Stem Cells

Efficient generation of cardiomyocytes from human pluripotent stem cells is critical for their regenerative applications. Microgravity and 3D culture can profoundly modulate cell proliferation and survival. Here, we engineered microscale progenitor cardiac spheres from human pluripotent stem cells a...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Jha, Rajneesh, Wu, Qingling, Singh, Monalisa, Preininger, Marcela K., Han, Pengcheng, Ding, Gouliang, Cho, Hee Cheol, Jo, Hanjoong, Maher, Kevin O., Wagner, Mary B., Xu, Chunhui
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4974658/
https://ncbi.nlm.nih.gov/pubmed/27492371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30956
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