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Contamination of DNase Preparations Confounds Analysis of the Role of DNA in Alum-Adjuvanted Vaccines

Aluminum salt (alum) adjuvants have been used for many years as adjuvants for human vaccines because they are safe and effective. Despite its widespread use, the means by which alum acts as an adjuvant remains poorly understood. Recently, it was shown that injected alum is rapidly coated with host c...

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Pubblicato in:J Immunol
Autori principali: Noges, Laura E., White, Janice, Cambier, John C., Kappler, John W., Marrack, Philippa
Natura: Artigo
Lingua:Inglês
Pubblicazione: AAI 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4974487/
https://ncbi.nlm.nih.gov/pubmed/27357147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501565
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