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Contamination of DNase Preparations Confounds Analysis of the Role of DNA in Alum-Adjuvanted Vaccines

Aluminum salt (alum) adjuvants have been used for many years as adjuvants for human vaccines because they are safe and effective. Despite its widespread use, the means by which alum acts as an adjuvant remains poorly understood. Recently, it was shown that injected alum is rapidly coated with host c...

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Detalles Bibliográficos
Publicado en:J Immunol
Main Authors: Noges, Laura E., White, Janice, Cambier, John C., Kappler, John W., Marrack, Philippa
Formato: Artigo
Idioma:Inglês
Publicado: AAI 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4974487/
https://ncbi.nlm.nih.gov/pubmed/27357147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501565
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