Mitochondrial Dynamics Controls T Cell Fate Through Metabolic Programming

Activated effector T (T(E)) cells augment anabolic pathways of metabolism, such as aerobic glycolysis, while memory T (T(M)) cells engage catabolic pathways, like fatty acid oxidation (FAO). However, signals that drive these differences remain unclear. Mitochondria are metabolic organelles that acti...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Cell
Main Authors: Buck, Michael D., O’Sullivan, David, Klein Geltink, Ramon I., Curtis, Jonathan D., Chang, Chih-Hao, Sanin, David E., Qiu, Jing, Kretz, Oliver, Braas, Daniel, van der Windt, Gerritje J.W., Chen, Qiongyu, Ching-Cheng Huang, Stanley, O’Neill, Christina M., Edelson, Brian T., Pearce, Edward J., Sesaki, Hiromi, Huber, Tobias B., Rambold, Angelika S., Pearce, Erika L.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4974356/
https://ncbi.nlm.nih.gov/pubmed/27293185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.05.035
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares