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Using the Ubiquitin-modified Proteome to Monitor Distinct and Spatially Restricted Protein Homeostasis Dysfunction

Protein homeostasis dysfunction has been implicated in the development and progression of aging related human pathologies. There is a need for the establishment of quantitative methods to evaluate global protein homoeostasis function. As the ubiquitin (ub) proteasome system plays a key role in regul...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Gendron, Joshua M., Webb, Kristofor, Yang, Bing, Rising, Lisa, Zuzow, Nathan, Bennett, Eric J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4974337/
https://ncbi.nlm.nih.gov/pubmed/27185884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M116.058420
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