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Mitochondrial dysfunction in the type 2 diabetic heart is associated with alterations in spatially distinct mitochondrial proteomes

Cardiac complications and heart failure are the leading cause of death in type 2 diabetic patients. Mitochondrial dysfunction is central in the pathogenesis of the type 2 diabetic heart. However, it is unclear whether this dysfunction is specific for a particular subcellular region. The purpose of t...

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Detalhes bibliográficos
Main Authors: Dabkowski, Erinne R., Baseler, Walter A., Williamson, Courtney L., Powell, Matthew, Razunguzwa, Trust T., Frisbee, Jefferson C., Hollander, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930393/
https://ncbi.nlm.nih.gov/pubmed/20543078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00267.2010
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