Reversal of mitochondrial proteomic loss in Type 1 diabetic heart with overexpression of phospholipid hydroperoxide glutathione peroxidase

Mitochondrial dysfunction is a contributor to diabetic cardiomyopathy. Previously, we observed proteomic decrements within the inner mitochondrial membrane (IMM) and matrix of diabetic cardiac interfibrillar mitochondria (IFM) correlating with dysfunctional mitochondrial protein import. The goal of...

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Detalhes bibliográficos
Main Authors: Baseler, Walter A., Dabkowski, Erinne R., Jagannathan, Rajaganapathi, Thapa, Dharendra, Nichols, Cody E., Shepherd, Danielle L., Croston, Tara L., Powell, Matthew, Razunguzwa, Trust T., Lewis, Sara E., Schnell, David M., Hollander, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Obesity, Diabetes and Energy Homeostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627941/
https://ncbi.nlm.nih.gov/pubmed/23408027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00249.2012
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