Metformin Reduces Bleomycin-induced Pulmonary Fibrosis in Mice

Metformin has anti-inflammatory and anti-fibrotic effects. We investigated whether metformin has an inhibitory effect on bleomycin (BLM)-induced pulmonary fibrosis in a murine model. A total of 62 mice were divided into 5 groups: control, metformin (100 mg/kg), BLM, and BLM with metformin (50 mg/kg...

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Bibliographic Details
Published in:J Korean Med Sci
Main Authors: Choi, Sun Mi, Jang, An-Hee, Kim, Hyojin, Lee, Kyu Hwa, Kim, Young Whan
Format: Artigo
Language:Inglês
Published: The Korean Academy of Medical Sciences 2016
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4974183/
https://ncbi.nlm.nih.gov/pubmed/27510385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3346/jkms.2016.31.9.1419
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