Metformin ameliorates bleomycin-induced pulmonary fibrosis in mice by suppressing IGF-1

Idiopathic pulmonary fibrosis (IPF) is a devastating disease, which is characterized by the progressive deterioration in lung function. In the pathogenesis of IPF, insulin-like growth factor-1 (IGF-1) has been found to be heavily involved. Metformin, a commonly used oral antidiabetic agent, is known...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Am J Transl Res
Main Authors: Xiao, Huijuan, Huang, Xiaoxi, Wang, Shiyao, Liu, Zheng, Dong, Run, Song, Dingyun, Dai, Huaping
Format: Artigo
Jezik:Inglês
Izdano: e-Century Publishing Corporation 2020
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7137034/
https://ncbi.nlm.nih.gov/pubmed/32269725
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