Defining KIR and HLA Class I Genotypes at Highest Resolution via High-Throughput Sequencing

The physiological functions of natural killer (NK) cells in human immunity and reproduction depend upon diverse interactions between killer cell immunoglobulin-like receptors (KIRs) and their HLA class I ligands: HLA-A, HLA-B, and HLA-C. The genomic regions containing the KIR and HLA class I genes a...

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Udgivet i:Am J Hum Genet
Main Authors: Norman, Paul J., Hollenbach, Jill A., Nemat-Gorgani, Neda, Marin, Wesley M., Norberg, Steven J., Ashouri, Elham, Jayaraman, Jyothi, Wroblewski, Emily E., Trowsdale, John, Rajalingam, Raja, Oksenberg, Jorge R., Chiaroni, Jacques, Guethlein, Lisbeth A., Traherne, James A., Ronaghi, Mostafa, Parham, Peter
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4974113/
https://ncbi.nlm.nih.gov/pubmed/27486779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2016.06.023
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