Defining KIR and HLA Class I Genotypes at Highest Resolution via High-Throughput Sequencing

The physiological functions of natural killer (NK) cells in human immunity and reproduction depend upon diverse interactions between killer cell immunoglobulin-like receptors (KIRs) and their HLA class I ligands: HLA-A, HLA-B, and HLA-C. The genomic regions containing the KIR and HLA class I genes a...

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Publicado en:Am J Hum Genet
Autores principales: Norman, Paul J., Hollenbach, Jill A., Nemat-Gorgani, Neda, Marin, Wesley M., Norberg, Steven J., Ashouri, Elham, Jayaraman, Jyothi, Wroblewski, Emily E., Trowsdale, John, Rajalingam, Raja, Oksenberg, Jorge R., Chiaroni, Jacques, Guethlein, Lisbeth A., Traherne, James A., Ronaghi, Mostafa, Parham, Peter
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4974113/
https://ncbi.nlm.nih.gov/pubmed/27486779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2016.06.023
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