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Estimation after subpopulation selection in adaptive seamless trials

During the development of new therapies, it is not uncommon to test whether a new treatment works better than the existing treatment for all patients who suffer from a condition (full population) or for a subset of the full population (subpopulation). One approach that may be used for this objective...

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Bibliografiske detaljer
Udgivet i:Stat Med
Main Authors: Kimani, Peter K., Todd, Susan, Stallard, Nigel
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973856/
https://ncbi.nlm.nih.gov/pubmed/25903293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.6506
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