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Changes in protein structure monitored by use of gas‐phase hydrogen/deuterium exchange
The study of protein conformation by solution‐phase hydrogen/deuterium exchange (HDX) coupled to MS is well documented. This involves monitoring the exchange of backbone amide protons with deuterium and provides details concerning the protein's tertiary structure. However, undesired back‐exchan...
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| Publicado no: | Proteomics |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4973844/ https://ncbi.nlm.nih.gov/pubmed/25603979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201400440 |
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