Soluble flagellin coimmunization attenuates Th1 priming to Salmonella and clearance by modulating dendritic cell activation and cytokine production

Soluble flagellin (sFliC) from Salmonella Typhimurium (STm) can induce a Th2 response to itself and coadministered antigens through ligation of TLR5. These properties suggest that sFliC could potentially modulate responses to Th1 antigens like live STm if both antigens are given concurrently. After...

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Detalhes bibliográficos
Publicado no:Eur J Immunol
Main Authors: Flores‐Langarica, Adriana, Bobat, Saeeda, Marshall, Jennifer L., Yam‐Puc, Juan Carlos, Cook, Charlotte N., Serre, Karine, Kingsley, Robert A., Flores‐Romo, Leopoldo, Uematsu, Satoshi, Akira, Shizuo, Henderson, Ian R., Toellner, Kai M., Cunningham, Adam F.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Immunity to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973836/
https://ncbi.nlm.nih.gov/pubmed/26036767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201545564
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