Probucol inhibits LPS-induced microglia activation and ameliorates brain ischemic injury in normal and hyperlipidemic mice

AIM: Increasing evidence suggests that probucol, a lipid-lowering agent with anti-oxidant activities, may be useful for the treatment of ischemic stroke with hyperlipidemia via reduction in cholesterol and neuroinflammation. In this study we examined whether probucol could protect against brain isch...

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Publicat a:Acta Pharmacol Sin
Autors principals: Jung, Yeon Suk, Park, Jung Hwa, Kim, Hyunha, Kim, So Young, Hwang, Ji Young, Hong, Ki Whan, Bae, Sun Sik, Choi, Byung Tae, Lee, Sae-Won, Shin, Hwa Kyoung
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973385/
https://ncbi.nlm.nih.gov/pubmed/27345627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2016.51
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