Probucol inhibits LPS-induced microglia activation and ameliorates brain ischemic injury in normal and hyperlipidemic mice

AIM: Increasing evidence suggests that probucol, a lipid-lowering agent with anti-oxidant activities, may be useful for the treatment of ischemic stroke with hyperlipidemia via reduction in cholesterol and neuroinflammation. In this study we examined whether probucol could protect against brain isch...

Full description

Saved in:
Bibliographic Details
Published in:Acta Pharmacol Sin
Main Authors: Jung, Yeon Suk, Park, Jung Hwa, Kim, Hyunha, Kim, So Young, Hwang, Ji Young, Hong, Ki Whan, Bae, Sun Sik, Choi, Byung Tae, Lee, Sae-Won, Shin, Hwa Kyoung
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
Subjects:
Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973385/
https://ncbi.nlm.nih.gov/pubmed/27345627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2016.51
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items