Transcriptome sequencing reveals that LPS-triggered transcriptional responses in established microglia BV2 cell lines are poorly representative of primary microglia

BACKGROUND: Microglia are resident myeloid cells in the CNS that are activated by infection, neuronal injury, and inflammation. Established BV2 microglial cell lines have been the primary in vitro models used to study neuroinflammation for more than a decade because they reduce the requirement of co...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Das, Amitabh, Kim, Sun Hwa, Arifuzzaman, Sarder, Yoon, Taeho, Chai, Jin Choul, Lee, Young Seek, Park, Kyoung Sun, Jung, Kyoung Hwa, Chai, Young Gyu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4940985/
https://ncbi.nlm.nih.gov/pubmed/27400875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0644-1
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