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Grafting voltage and pharmacological sensitivity in potassium channels
A classical voltage-gated ion channel consists of four voltage-sensing domains (VSDs). However, the roles of each VSD in the channels remain elusive. We developed a GVTDT (Graft VSD To Dimeric TASK3 channels that lack endogenous VSDs) strategy to produce voltage-gated channels with a reduced number...
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| Publié dans: | Cell Res |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4973326/ https://ncbi.nlm.nih.gov/pubmed/27174053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2016.57 |
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