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Structural analysis of a function-associated loop mutant of the substrate-recognition domain of Fbs1 ubiquitin ligase

The SCF ubiquitin ligase comprises four components: Skp1, Cul1, Rbx1 and a variable-subunit F-box protein. The F-box protein Fbs1, which recognizes the N-linked glycoproteins, is involved in the endoplasmic reticulum-associated degradation pathway. Although FBG3, another F-box protein, shares 51% se...

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Bibliographic Details
Published in:Acta Crystallogr F Struct Biol Commun
Main Authors: Nishio, Kazuya, Yoshida, Yukiko, Tanaka, Keiji, Mizushima, Tsunehiro
Format: Artigo
Language:Inglês
Published: International Union of Crystallography 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973303/
https://ncbi.nlm.nih.gov/pubmed/27487926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X16011018
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