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Crystal structure of the substrate-recognition domain of the Shigella E3 ligase IpaH9.8

Infectious diseases caused by bacteria have significant impacts on global public health. During infection, pathogenic bacteria deliver a variety of virulence factors, called effectors, into host cells. The Shigella effector IpaH9.8 functions as an ubiquitin ligase, ubiquitinating the NF-κB essential...

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Detalhes bibliográficos
Publicado no:Acta Crystallogr F Struct Biol Commun
Main Authors: Takagi, Kenji, Kim, Minsoo, Sasakawa, Chihiro, Mizushima, Tsunehiro
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822982/
https://ncbi.nlm.nih.gov/pubmed/27050259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X16002715
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