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2.4 Å resolution crystal structure of human TRAP1(NM), the Hsp90 paralog in the mitochondrial matrix

TRAP1 is an organelle-specific Hsp90 paralog that is essential for neoplastic growth. As a member of the Hsp90 family, TRAP1 is presumed to be a general chaperone facilitating the late-stage folding of Hsp90 client proteins in the mitochondrial matrix. Interestingly, TRAP1 cannot replace cytosolic H...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Acta Crystallogr D Struct Biol
Egile Nagusiak: Sung, Nuri, Lee, Jungsoon, Kim, Ji-Hyun, Chang, Changsoo, Tsai, Francis T. F., Lee, Sukyeong
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: International Union of Crystallography 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973209/
https://ncbi.nlm.nih.gov/pubmed/27487821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2059798316009906
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