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2.4 Å resolution crystal structure of human TRAP1(NM), the Hsp90 paralog in the mitochondrial matrix
TRAP1 is an organelle-specific Hsp90 paralog that is essential for neoplastic growth. As a member of the Hsp90 family, TRAP1 is presumed to be a general chaperone facilitating the late-stage folding of Hsp90 client proteins in the mitochondrial matrix. Interestingly, TRAP1 cannot replace cytosolic H...
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| Publicado en: | Acta Crystallogr D Struct Biol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
International Union of Crystallography
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4973209/ https://ncbi.nlm.nih.gov/pubmed/27487821 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2059798316009906 |
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