Expression of phosphorylated eIF4E-binding protein 1, but not of eIF4E itself, predicts survival in male breast cancer

BACKGROUND: Male breast cancer is rare and treatment is based on data from females. High expression/activity of eukaryotic initiation factor 4E (eIF4E) denotes a poor prognosis in female breast cancer, and the eIF4E pathway has been targeted therapeutically. Eukaryotic initiation factor 4E activity...

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Veröffentlicht in:Br J Cancer
Hauptverfasser: Millican-Slater, Rebecca A, Sayers, Craig D, Hanby, Andrew M, Hughes, Thomas A
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Molecular Diagnostics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973151/
https://ncbi.nlm.nih.gov/pubmed/27280636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.178
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