Synergistic activation of eIF4A by eIF4B and eIF4G

eIF4A is a key component in eukaryotic translation initiation; however, it has not been clear how auxiliary factors like eIF4B and eIF4G stimulate eIF4A and how this contributes to the initiation process. Based on results from isothermal titration calorimetry, we propose a two-site model for eIF4A b...

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Bibliografiske detaljer
Main Authors: Nielsen, Klaus H., Behrens, Manja A., He, Yangzi, Oliveira, Cristiano L. P., Sottrup Jensen, Lars, Hoffmann, Søren V., Pedersen, Jan S., Andersen, Gregers R.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2011
Fag:
Molecular Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074137/
https://ncbi.nlm.nih.gov/pubmed/21113024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq1206
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