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Evolutionary changes in the Leishmania eIF4F complex involve variations in the eIF4E–eIF4G interactions
Translation initiation in eukaryotes is mediated by assembly of the eIF4F complex over the m(7)GTP cap structure at the 5′-end of mRNAs. This requires an interaction between eIF4E and eIF4G, two eIF4F subunits. The Leishmania orthologs of eIF4E are structurally diverged from their higher eukaryote c...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Oxford University Press
2009
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2691829/ https://ncbi.nlm.nih.gov/pubmed/19321500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp190 |
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