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Evolutionary changes in the Leishmania eIF4F complex involve variations in the eIF4E–eIF4G interactions

Translation initiation in eukaryotes is mediated by assembly of the eIF4F complex over the m(7)GTP cap structure at the 5′-end of mRNAs. This requires an interaction between eIF4E and eIF4G, two eIF4F subunits. The Leishmania orthologs of eIF4E are structurally diverged from their higher eukaryote c...

詳細記述

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書誌詳細
主要な著者: Yoffe, Yael, Léger, Mélissa, Zinoviev, Alexandra, Zuberek, Joanna, Darzynkiewicz, Edward, Wagner, Gerhard, Shapira, Michal
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2691829/
https://ncbi.nlm.nih.gov/pubmed/19321500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp190
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