Phosphorylation of eIF4E serine 209 is associated with tumour progression and reduced survival in malignant melanoma

BACKGROUND: Melanoma is a disease that primarily arises in the skin but is a derivative of the neural crest. Eukaryotic translation initiation factor 4E (eIF4E) regulates translation of multiple malignancy-associated mRNAs and is overexpressed in many epithelial tumours. However, expression in human...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Carter, Julia H, Deddens, James A, Spaulding IV, Nelson Reed, Lucas, Denise, Colligan, Bruce M, Lewis, Thomas Grant, Hawkins, Elyse, Jones, Jordan, Pemberton, Jackson O, Douglass, Larry E, Graff, Jeremy R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815768/
https://ncbi.nlm.nih.gov/pubmed/26882068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.450
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