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Neddylation requires glycyl-tRNA synthetase to protect activated E2
Neddylation is a post-translational modification that controls cell cycle and proliferation by conjugating the ubiquitin-like protein NEDD8 to specific targets. Here we report that glycyl-tRNA synthetase (GlyRS), an essential enzyme for protein synthesis, also plays a critical role in neddylation. I...
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| Publicat a: | Nat Struct Mol Biol |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4972647/ https://ncbi.nlm.nih.gov/pubmed/27348078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3250 |
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