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CDKN2A-independent role of BMI1 in promoting growth and survival of Ph+ acute lymphoblastic leukemia
BMI1 is a key component of the PRC1 complex (polycomb repressive complex-1) required for maintenance of normal and cancer stem cells. Its aberrant expression is detected in chronic myeloid leukemia and Ph+ acute lymphoblastic leukemia (ALL), but no data exist on BMI1 requirement in ALL cells. We sho...
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| Publicado no: | Leukemia |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4972639/ https://ncbi.nlm.nih.gov/pubmed/27125204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2016.70 |
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