Regulation of Retinoic Acid Inducible Gene-I (RIG-I) Activation by the Histone Deacetylase 6

Retinoic acid inducible gene-I (RIG-I) is a cytosolic pathogen recognition receptor that initiates the immune response against many RNA viruses. Upon RNA ligand binding, RIG-I undergoes a conformational change facilitating its homo-oligomerization and activation that results in its translocation fro...

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Bibliografiske detaljer
Udgivet i:EBioMedicine
Main Authors: Liu, Helene Minyi, Jiang, Fuguo, Loo, Yueh Ming, Hsu, ShuZhen, Hsiang, Tien-Ying, Marcotrigiano, Joseph, Gale, Michael
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972567/
https://ncbi.nlm.nih.gov/pubmed/27372014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.06.015
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