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Resolving Isomeric Glycopeptide Glycoforms with Hydrophilic Interaction Chromatography (HILIC)

The ability to resolve glycans while attached to tryptic peptides would greatly facilitate glycoproteomics, as this would enable site-specific glycan characterization. Peptide/glycopeptide separations are typically performed using reversed-phase liquid chromatography (RPLC), where retention is drive...

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Pubblicato in:J Biomol Tech
Autori principali: Huang, Yining, Nie, Yongxin, Boyes, Barry, Orlando, Ron
Natura: Artigo
Lingua:Inglês
Pubblicazione: Association of Biomolecular Resource Facilities 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972402/
https://ncbi.nlm.nih.gov/pubmed/27582638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7171/jbt.16-2703-003
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