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Peptide Retention Prediction Using Hydrophilic Interaction Liquid Chromatography Coupled to Mass Spectrometry

A model that predicts retention for peptides using a HALO(®) penta-HILIC column and gradient elution was created. Coefficients for each amino acid were derived using linear regression analysis and these coefficients can be summed to predict the retention of peptides. This model has a high correlatio...

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Detalles Bibliográficos
Publicado en:J Chromatogr A
Autores principales: Badgett, Majors J., Boyes, Barry, Orlando, Ron
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5805588/
https://ncbi.nlm.nih.gov/pubmed/29338870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chroma.2017.12.055
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