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Design strategies to address the effect of hydrophobic epitope on stability and in vitro assembly of modular virus‐like particle

Virus‐like particles (VLPs) and capsomere subunits have shown promising potential as safe and effective vaccine candidates. They can serve as platforms for the display of foreign epitopes on their surfaces in a modular architecture. Depending on the physicochemical properties of the antigenic module...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Tekewe, Alemu, Connors, Natalie K., Middelberg, Anton P. J., Lua, Linda H. L.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972206/
https://ncbi.nlm.nih.gov/pubmed/27222486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2953
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