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Design strategies to address the effect of hydrophobic epitope on stability and in vitro assembly of modular virus‐like particle

Virus‐like particles (VLPs) and capsomere subunits have shown promising potential as safe and effective vaccine candidates. They can serve as platforms for the display of foreign epitopes on their surfaces in a modular architecture. Depending on the physicochemical properties of the antigenic module...

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Publicado en:Protein Sci
Autores principales: Tekewe, Alemu, Connors, Natalie K., Middelberg, Anton P. J., Lua, Linda H. L.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972206/
https://ncbi.nlm.nih.gov/pubmed/27222486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2953
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