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Virus assembly occurs following a pH- or Ca(2+)-triggered switch in the thermodynamic attraction between structural protein capsomeres

Viral self-assembly is of tremendous virological and biomedical importance. Although theoretical and crystallographic considerations suggest that controlled conformational change is a fundamental regulatory mechanism in viral assembly, direct proof that switching alters the thermodynamic attraction...

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Detalhes bibliográficos
Main Authors: Chuan, Yap P., Fan, Yuan Y., Lua, Linda H. L., Middelberg, Anton P. J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842788/
https://ncbi.nlm.nih.gov/pubmed/19625304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2009.0175
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