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Firefly Luciferase Mutants Allow Substrate-Selective Bioluminescence Imaging in the Mouse Brain

Bioluminescence imaging is a powerful approach to visualize specific events occurring inside live mice. Animals can be made to glow in response to the expression of a gene, the activity of an enzyme, or the growth of a tumor. But bioluminescence requires the interaction of a luciferase enzyme with a...

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Détails bibliographiques
Publié dans:Angew Chem Int Ed Engl
Auteurs principaux: Adams, Spencer T., Mofford, David M., Kiran Kumar Reddy, G. S., Miller, Stephen C.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972182/
https://ncbi.nlm.nih.gov/pubmed/26991209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201511350
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