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Mitochondrial biogenesis meets chemoresistance in BRAF-mutant melanoma

The acquisition of resistance to current mitogen activated protein kinase (MAPK) inhibitors in B-Raf proto-oncogene, serine/threonine kinase (BRAF) mutant melanoma is almost inevitable. Our recent findings identify therapy-induced mitochondrial biogenesis (MitoBiogenesis) and aberrant tumor bioenerg...

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Publicado en:Mol Cell Oncol
Main Authors: Wu, Lawrence W., Zhang, Gao, Herlyn, Meenhard
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972122/
https://ncbi.nlm.nih.gov/pubmed/27652325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2016.1179381
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