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Evaluation of folate receptor 1 (FOLR1) mRNA expression, its specific promoter methylation and global DNA hypomethylation in type I and type II ovarian cancers

BACKGROUND: In this retrospective study we evaluated the respective correlations and clinical relevance of FOLR1 mRNA expression, FOLR1 promoter specific methylation and global DNA hypomethylation in type I and type II ovarian cancer. METHODS: Two hundred fifty four ovarian cancers, 13 borderline tu...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Notaro, Sara, Reimer, Daniel, Fiegl, Heidi, Schmid, Gabriel, Wiedemair, Annamarie, Rössler, Julia, Marth, Christian, Zeimet, Alain Gustave
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4971744/
https://ncbi.nlm.nih.gov/pubmed/27485273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2637-y
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